Vertex Pharmaceuticals Incorporated Ratios | P/E, ROE & Valuation

On the Key Ratios page for Vertex Pharmaceuticals Incorporated (VRTX), the latest P/E of 28.1 frames valuation, while ROE 23.93% and ROIC 17.74% indicates profitability and capital efficiency. Together with the current ratio of 3.02 and debt-to-equity 0.10, these signals help you judge whether valuation is supported by fundamentals across the historical rows.

Financial Performance Ratios

VRTX Historical Per Share Metrics

10 years
Metric (FY)TTM202420232022202120202019201820172016
Revenue per Share$48.23$42.80$38.30$34.87$29.39$23.88$16.21$11.98$10.00$6.99
Net Income per Share$17.07$-2.08$14.05$12.97$9.09$10.44$4.58$8.25$1.06$-0.46
Operating Cash Flow per Share$16.69$-1.91$13.73$16.13$10.26$12.52$6.11$5.00$3.40$0.97
Free Cash Flow per Share$14.60$-3.07$12.72$15.33$9.35$11.52$5.82$4.62$2.35$0.74
Cash per Share$28.52$23.75$43.53$42.09$29.20$25.63$14.83$12.46$8.39$5.89
Book Value per Share$76.20$63.73$68.22$54.33$39.19$33.43$23.70$17.44$8.21$5.48
Tangible Book Value per Share$70.27$56.29$60.74$47.72$33.75$28.03$18.24$17.24$7.89$4.11
Interest Debt per Share$7.86$6.91$3.31$3.73$3.99$3.81$2.81$2.44$2.72$3.79
CAPEX per Share$2.09$1.16$1.00$0.80$0.91$1.00$0.29$0.38$1.04$0.23

VRTX Historical Valuation Ratios

10 years
Metric (FY)TTM202420232022202120202019201820172016
Price to Earnings (P/E)28.06-193.6128.9722.2624.1622.6547.7720.1141.54-160.15
Price to Book (P/B)6.266.325.965.325.67.079.249.518.3815.52
Price to Sales (P/S)9.899.4110.628.287.479.913.513.8314.9910.54
Enterprise Value to EBITDA21.82207.4320.6914.5117.417.1634.4656.7350.92233.25
EV to Sales9.69.159.667.216.79.0812.9213.1514.5610.34
EV to Operating Cash Flow27.74-204.7826.9415.5819.217.3234.2631.5542.8874.55
EV to Free Cash Flow31.71-127.6429.0616.3921.0818.8235.9934.1161.8898.04
Enterprise Value$117.65B$100.88B$95.29B$64.35B$50.76B$56.35B$53.76B$40.08B$36.23B$17.60B

VRTX Historical Profitability Ratios

10 years
Metric (FY)TTM202420232022202120202019201820172016
Return on Equity (ROE)23.93%-3.26%20.59%23.88%23.19%31.22%19.34%47.28%12.99%-9.69%
Return on Invested Capital (ROIC)17.74%2.62%16.44%21.81%20.99%25.06%14.39%43.04%-26.07%0.51%
Return on Tangible Assets17.37%-2.60%17.40%20.18%19.47%26.20%17.02%33.85%7.60%-4.38%
Earnings Yield3.58%-0.52%3.45%4.49%4.14%4.42%2.09%4.98%0.71%-0.62%
Free Cash Flow Yield3.06%-0.76%3.13%5.31%4.26%4.87%2.66%2.79%1.57%1.00%
Dividend Yield0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%

VRTX Historical Liquidity & Financial Strength

10 years
Metric (FY)TTM202420232022202120202019201820172016
Current Ratio3.022.693.994.834.464.333.613.433.282.31
Interest Coverage463.67-7.6186.8978.645.2449.1220.4718.621.780.12
Income Quality0.980.920.981.241.131.21.330.619.22-2.81
Debt to Equity0.10.110.050.060.10.110.110.130.30.73
Debt to Assets7.50%7.76%3.56%4.96%7.20%7.93%7.95%9.40%17.10%29.05%
Net Debt to EBITDA-0.65-5.8-2.08-2.17-2-1.54-1.57-2.92-10.26-4.55

VRTX Historical Efficiency Ratios

10 years
Metric (FY)TTM202420232022202120202019201820172016
Receivables Turnover6.146.856.316.196.667.016.577.446.457.23
Payables Turnover3.443.713.463.554.644.756.253.693.723.42
Inventory Turnover0.951.271.712.352.562.623.273.292.462.71
Days Sales Outstanding59.4553.3157.8258.9454.7852.0855.5549.0756.6150.49
Days Payables Outstanding106.2498.49105.52102.6878.7276.8958.3898.9298.17106.57
Days of Inventory on Hand383.59287.47213.64155.62142.54139.19111.62110.84148.36134.59

VRTX Historical Market Metrics

10 years
Metric (FY)TTM202420232022202120202019201820172016
Enterprise Value to EBITDA21.82207.4320.6914.5117.417.1634.4656.7350.92233.25
Market Cap$121.16B$103.70B$104.86B$73.96B$56.59B$61.41B$56.21B$42.14B$37.29B$17.95B
Enterprise Value$117.65B$100.88B$95.29B$64.35B$50.76B$56.35B$53.76B$40.08B$36.23B$17.60B
Dividend Yield0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%
Payout Ratio0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%

Frequently Asked Questions

Is Vertex Pharmaceuticals Incorporated stock overvalued based on its P/E ratio?

On this page, VRTX's current P/E is 28.1, compared with a multi-year average around 41.9. A lower P/E versus its own history is often interpreted as relatively cheaper valuation (all else equal). In practice, the "why" matters: check whether the lower multiple is supported by profitability and earnings quality (for example, ROE/ROIC and income quality in the table), or whether it reflects weaker fundamentals.

What is Vertex Pharmaceuticals Incorporated market cap?

Market cap is the market value of a company's equity and is commonly calculated as share price multiplied by shares outstanding. The latest market cap shown in the table is $121.16B. Pair market cap with valuation multiples (P/E, P/B, P/S) so you can evaluate whether size also corresponds with "quality" and profitability. For a wider view across stocks, you can also use the stock screener.

What is a good P/E ratio for Vertex Pharmaceuticals Incorporated compared to its industry?

There isn't one universal "good" P/E - P/E should be judged against the business model and expected growth for its sector. A practical approach is: (1) compare the P/E on this page to Vertex Pharmaceuticals Incorporated's own historical range (shown across the table's rows), and (2) benchmark against peer companies using the Screener's P/E filters and the Peers Comparison/Compare tools. If profitability (ROE/ROIC) and cash-flow strength are improving, a higher P/E can be more defensible; if returns are slipping, even a lower P/E may be a value trap.

How does Vertex Pharmaceuticals Incorporated compare to its competitors in key financial ratios?

The fastest way to compare Vertex Pharmaceuticals Incorporated with competitors is to use the built-in "Peers Comparison" section on this page and the Compare tool. Focus on a small set of ratios that work together: P/E for valuation, ROE/ROIC for profitability and capital efficiency, current ratio and interest coverage for liquidity and solvency, and debt-to-equity for leverage risk. When you see Vertex Pharmaceuticals Incorporated outperform peers on profitability while keeping valuation and leverage reasonable, it often signals stronger fundamentals.

Is Vertex Pharmaceuticals Incorporated financially strong based on its ratios?

To assess whether Vertex Pharmaceuticals Incorporated is financially strong, review both profitability and balance-sheet risk together. Current ratio is about 3.02, which is above 1.0 and can indicate more comfortable short-term liquidity. Interest coverage is about 463.67, implying a stronger ability to cover interest expenses. Debt-to-equity is about 0.10, suggesting leverage is more moderate relative to a high-debt profile. Then confirm the same story is supported by ROE/ROIC (quality of earnings) and by cash-flow backed metrics in the table.

What do Vertex Pharmaceuticals Incorporated's financial ratios say about its future growth?

Ratios are a way to see what the business is likely to sustain. Look for upward trends in profitability metrics (ROE and ROIC), improving earnings/cash-flow backed measures, and stable or strengthening liquidity. If Vertex Pharmaceuticals Incorporated is sustaining strong returns (for example ROE at 23.93% and ROIC at 17.74%) while debt levels and interest coverage remain manageable, growth expectations may be more credible. If valuation multiples expand while returns weaken, the market may be pricing optimistic growth ahead of results.