Alnylam Pharmaceuticals, Inc. Ratios | P/E, ROE & Valuation

On the Key Ratios page for Alnylam Pharmaceuticals, Inc. (ALNY), the latest P/E of 38.0 frames valuation, while ROE 93.61% and ROIC 24.43% indicates profitability and capital efficiency. Together with the current ratio of 3.05 and debt-to-equity 0.94, these signals help you judge whether valuation is supported by fundamentals across the historical rows.

Financial Performance Ratios

ALNY Historical Per Share Metrics

10 years
Metric (FY)TTM202420232022202120202019201820172016
Revenue per Share$36.06$17.61$14.64$8.53$7.13$4.29$2.01$0.74$0.99$0.55
Net Income per Share$6.06$-2.18$-3.52$-9.30$-7.20$-7.46$-8.11$-7.57$-5.42$-4.79
Operating Cash Flow per Share$4.76$-0.07$0.83$-4.45$-5.42$-5.35$-2.55$-5.59$-4.23$-3.59
Free Cash Flow per Share$4.07$-0.33$0.34$-5.04$-6.06$-5.96$-3.83$-6.85$-5.38$-4.35
Cash per Share$24.83$21.11$19.53$18.02$20.56$16.30$14.06$10.78$18.67$7.32
Book Value per Share$10.16$0.53$-1.77$-1.30$4.97$8.84$13.17$12.94$19.51$10.75
Tangible Book Value per Share$10.16$0.53$-1.77$-1.30$4.97$8.84$13.17$12.94$19.51$10.75
Interest Debt per Share$11.95$11.26$11.42$12.13$9.63$5.27$2.78$0.30$0.33$1.75
CAPEX per Share$0.69$0.27$0.50$0.59$0.64$0.61$1.28$1.26$1.15$0.75

ALNY Historical Valuation Ratios

10 years
Metric (FY)TTM202420232022202120202019201820172016
Price to Earnings (P/E)38-107.99-54.31-25.57-23.55-17.41-14.2-9.63-23.44-7.81
Price to Book (P/B)22.81447.73-108.36-182.7834.1514.718.755.636.513.48
Price to Sales (P/S)6.4613.3613.0827.8823.7930.3257.2697.91127.9667.96
Enterprise Value to EBITDA26.57-169.79-94.49-31.7-30.63-20.33-14.22-9.21-22.31-7.72
EV to Sales6.3713.5113.3528.312430.3756.1692.7121.1167.03
EV to Operating Cash Flow48.2-3653.41234.27-54.27-31.58-24.34-44.32-12.34-28.45-10.27
EV to Free Cash Flow56.36-713.03581.74-47.89-28.22-21.84-29.48-10.07-22.36-8.49
Enterprise Value$30.58B$30.37B$24.40B$29.37B$20.26B$14.97B$12.34B$6.94B$10.89B$3.16B

ALNY Historical Profitability Ratios

10 years
Metric (FY)TTM202420232022202120202019201820172016
Return on Equity (ROE)93.61%-414.62%199.53%714.91%-144.99%-84.46%-61.59%-58.49%-27.79%-44.57%
Return on Invested Capital (ROIC)24.43%-4.06%-9.87%-27.94%-23.73%-29.07%-45.42%-58.45%-27.02%-37.54%
Return on Tangible Assets14.54%-6.56%-11.49%-31.90%-23.41%-25.19%-37.00%-48.36%-24.61%-32.48%
Earnings Yield2.62%-0.93%-1.84%-3.91%-4.25%-5.74%-7.04%-10.38%-4.27%-12.80%
Free Cash Flow Yield1.75%-0.14%0.18%-2.12%-3.57%-4.59%-3.33%-9.40%-4.23%-11.62%
Dividend Yield0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%

ALNY Historical Liquidity & Financial Strength

10 years
Metric (FY)TTM202420232022202120202019201820172016
Current Ratio3.052.783.083.514.044.474.876.6912.235.1
Interest Coverage3.08-1.25-2.33-5.03-4.95-9.80000
Income Quality0.790.03-0.240.480.750.720.310.740.780.75
Debt to Equity0.9419.32-5.92-8.341.70.510.210.020.020.16
Debt to Assets22.80%30.57%34.08%37.23%27.38%15.30%12.69%1.91%1.50%11.88%
Net Debt to EBITDA-0.38-1.84-1.91-0.49-0.27-0.030.280.521.260.11

ALNY Historical Efficiency Ratios

10 years
Metric (FY)TTM202420232022202120202019201820172016
Receivables Turnover5.265.555.584.364.250.825.113.992.642.02
Payables Turnover9.023.665.591.721.911.50.50.030.470
Inventory Turnover10.034.123.481.311.621.040.440.0700
Days Sales Outstanding69.3565.865.4483.7285.85446.1471.4491.41138.03180.6
Days Payables Outstanding40.4699.865.28212.09191.24243.01726.512094.02774.260
Days of Inventory on Hand36.3888.62104.82278.83224.93351.67820.654875.0400

ALNY Historical Market Metrics

10 years
Metric (FY)TTM202420232022202120202019201820172016
Enterprise Value to EBITDA26.57-169.79-94.49-31.7-30.63-20.33-14.22-9.21-22.31-7.72
Market Cap$31.02B$30.04B$23.91B$28.92B$20.09B$14.94B$12.58B$7.33B$11.50B$3.20B
Enterprise Value$30.58B$30.37B$24.40B$29.37B$20.26B$14.97B$12.34B$6.94B$10.89B$3.16B
Dividend Yield0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%
Payout Ratio0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%

Frequently Asked Questions

How does Alnylam Pharmaceuticals, Inc.’s P/E ratio compare with its history?

On this page, ALNY's current P/E is 38.0, compared with a multi-year average around 38.0. When the current P/E sits near its historical average, the multiple is close to that range. Look at trend direction in profitability and cash-flow rows, plus liquidity and leverage, rather than treating the P/E in isolation.

What is Alnylam Pharmaceuticals, Inc. market cap?

Market cap is the market value of a company's equity and is commonly calculated as share price multiplied by shares outstanding. The latest market cap shown in the table is $31.02B. Pair market cap with valuation multiples (P/E, P/B, P/S) so you can evaluate whether size also corresponds with "quality" and profitability. For a wider view across stocks, you can also use the stock screener.

How does Alnylam Pharmaceuticals, Inc.’s P/E compare with its industry?

There is no P/E Tickerplace rates as good. Compare the P/E on this page with Alnylam Pharmaceuticals, Inc.'s own historical range (in the table) and with peers via the Screener and Compare tools. A higher or lower multiple versus peers is a calculated gap, not a recommendation.

How does Alnylam Pharmaceuticals, Inc. compare to its competitors in key financial ratios?

The fastest way to compare Alnylam Pharmaceuticals, Inc. with competitors is to use the built-in "Peers Comparison" section on this page and the Compare tool. Focus on a small set of ratios that work together: P/E for valuation, ROE/ROIC for profitability and capital efficiency, current ratio and interest coverage for liquidity and solvency, and debt-to-equity for leverage risk. When you see Alnylam Pharmaceuticals, Inc. outperform peers on profitability while keeping valuation and leverage reasonable, it often signals stronger fundamentals.

What do Alnylam Pharmaceuticals, Inc.'s liquidity and leverage ratios show?

Liquidity and leverage figures on this page are published ratios, not a verdict that Alnylam Pharmaceuticals, Inc. is financially strong. Current ratio is about 3.05, which is above 1.0 and can indicate more comfortable short-term liquidity. Interest coverage is about 3.08, implying a stronger ability to cover interest expenses. Debt-to-equity is about 0.94, suggesting leverage is more moderate relative to a high-debt profile. Pair them with ROE/ROIC and cash-flow rows in the table. Tickerplace does not rate the company as a good or poor investment.

What do Alnylam Pharmaceuticals, Inc.'s financial ratios say about its future growth?

Ratios are a way to see what the business is likely to sustain. Look for upward trends in profitability metrics (ROE and ROIC), improving earnings/cash-flow backed measures, and stable or strengthening liquidity. If Alnylam Pharmaceuticals, Inc. is sustaining strong returns (for example ROE at 93.61% and ROIC at 24.43%) while debt levels and interest coverage remain manageable, growth expectations may be more credible. If valuation multiples expand while returns weaken, the market may be pricing optimistic growth ahead of results.