Spyre Therapeutics, Inc. (SYRE) is currently Overvalued by 34714.01%

Spyre Therapeutics, Inc. (SYRE) appears overvalued by approximately 34714.01% based on our live valuation percent and intrinsic value estimate derived from DCF, P/E Multiple, and P/S Multiple models. Valuation can still differ across analyst models, growth expectations, and risk assumptions.

Downside (live) 34714.01% (from live valuation API)
Confidence (live) 8.5/10 (High conviction overvalued)

Confidence Score is based on the magnitude of upside or downside vs intrinsic value.

Fair value estimate

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Current price

$94.23

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Why is Spyre Therapeutics, Inc. overvalued or undervalued?

Intrinsic value work anchors Spyre Therapeutics, Inc. on owner earnings and balance-sheet capacity; the current quote trades below that anchor, which frames the stock as relatively cheap on a fundamentals-first view.

Versus historical valuation bands, SYRE is closer to the lower end of where this business has traded when profitability and growth were comparable—useful context before reading any single headline multiple.

Forward market expectations are muted: the price does not require heroic assumptions to converge with our fair-value zone, but sector peers and macro rates still deserve a quick sanity check on the company page.

Key metrics

P/E ratio: 42.1x
Revenue growth (TTM y/y): 3%
Profit margin: 27.2%
Fair value (model): Unlock

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Frequently asked questions — SYRE

Is SYRE overvalued right now?

Based on our 2026 models, Spyre Therapeutics, Inc. (SYRE) appears overvalued at $94.23 with roughly 34714.0% downside versus fair value. Confirm with valuation ratios and financials before acting.

What is Spyre Therapeutics, Inc.'s intrinsic value?

Our DCF, P/E Multiple, and P/S Multiple models estimate whether SYRE trades above or below fair value. At $94.23, Spyre Therapeutics, Inc. currently looks overvalued on this snapshot. Tickerplace Pro unlocks the full dollar fair value estimate.

How is Spyre Therapeutics, Inc.'s intrinsic value calculated?

Tickerplace calculates SYRE's fair value using Discounted Cash Flow (DCF), P/E Multiple, and P/S Multiple models. We compare the resulting intrinsic value estimate to the live market price to flag undervalued or overvalued positioning.

Is SYRE undervalued right now?

A stock is undervalued when price sits below a supportable fair value range. Check whether SYRE's gap aligns with fundamentals using the ratios and financial links on this page.

Peers for SYRE: open their overvalued / undervalued view.

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